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Traditionally, clinicians have relied heavily on the use of non-steroidal anti-inflammatory drugs NSAIDs to treat the pain of OA, as numerous studies have proven these agents to be effective. The cardiovascular, gastrointestinal, renal and hepatic toxicities of NSAIDs have limited their use, particularly in the elderly. Several other topical, oral and intra-articular agents are available today, with use limited by efficacy and side effect profiles. Many non-pharmacologic approaches are available but underused, and may be attractive choices to avoid poly-pharmacy in older patients. We will attempt to highlight the evidence behind available non-surgical therapies for OA while paying specific attention to issues in geriatric patients.

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Watch ' Just Between Lovers ' with our fast and smooth mobile player, optimized for your phone and tablet. A building collapse ties the fates of three young people years later. Ten years ago, the S Mall collapsed due to shoddy construction, killing 48 people inside. Lee Kang Doo Junho was there waiting for his father, who was an electrician doing work on the building. Years later, Joo Won is an architect who is working on a new project to replace the former S Mall.

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Between sentences, she pierces my skin, meticulously arranging each needle to create a starburst design on my right shoulder. When she removes the needles, she wipes my blood with pages torn from the book. As I continue to bleed, she smiles mischievously and licks me clean. How could I have enjoyed something so sick? I feel like an insect sinking into resin, helpless against the weight of my sadness.